Bayesian method for filtering out mRNA turnover rate bias from siRNA knockdown measurements

Abstract siRNA performance prediction calculations for a given siRNA may be divided into two broad categories: functions of the siRNA’s sequence, hereafter referred to as “intrinsic” properties of the siRNA, and functions of the target mRNA, hereafter referred to as “extrinsic” properties of the siRNA. When training a statistical or machine learning model to select […]

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the science of gender identity (part 3: psychology)

This is the third post in a multi-part series surveying the current science of gender identity, particularly with regard to the transgendered population. My first post on the subject covered proposed genetic associations and corresponding research. The second post on the matter discussed observed differences in brain anatomy between transgendered and cisgendered individuals. Here I […]

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the science of gender identity (part 2: brain anatomy)

This is the second post in a mult-part series surveying the current science of gender identity, particularly with regard to the transgendered population. In my previous post I discussed the proposed genetic associations and corresponding research. A future post, if I can find sufficient data, will address neuropsychology research related to the transgender experience. Here […]

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