fast genomic coordinate comparison using PostgreSQL’s geometric operators

PostgreSQL provides operators for comparing geometric data types, for example for computing whether two boxes overlap or whether one box contains another. Such operators are quick compared to similar calculations implemented using normal comparison operators, which I’ll demonstrate below. Here I show use of such geometric data types and operators for determining whether one segment […]

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werewolf transcriptome conjecture

Lycanthropy—the sudden transformation of individuals into wolf-human chimeras during full moon periods—remains one of the least understood medical conditions persisting today. Researchers find investigation of the phenomenon doubly confounded by social stigma (who wants to tell a scientist that they are a werewolf?) and sampling difficulty (how many werewolves will actually sit still for a […]

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