maximized entropy of a finite distribution

I received the following tweet yesterday from @ProbFact and decided to check it out in more detail: Two-Dimensional Case I generated the following test to investigate the claim: Create four category discrete distributions where two of the categories have 0.25 probability each, and the third category probability varies between 0.1 and 0.4. The fourth category’s […]

examining mRNA complexity by annotation region using MapReduce

I became interested in how annotated mRNA regions (e.g., 5′ UTR, coding, and 3′ UTR) vary in information content, speculating that coding regions (CDS) of transcripts will be generally more complex than other regions due to their role in specifying protein recipes. Measuring sequence complexity using Shannon entropy validated this hypothesis, at least with regard […]