simulating RNA-seq read counts

The Challenge I want to explore the statistics of RNA sequencing (RNA-seq) on next-generation sequencing (NGS) platforms in greater detail, so I thought I’d start by simulating read counts to experiment with. This post details how I constructed a simulated set of read counts, examines its concordance with the expected negative binomial distribution of the […]

test driving the Seven Bridges Genomics bioinformatics platform

I recently examined the Seven Bridges Genomics (SBG) platform, building and running a short-read alignment pipeline. Overall, I am impressed by the software. Here I describe my test of the program and then report on my investigation of how it works. Test Drive The test pipeline I devised consisted of two steps, FastQC analysis of […]